منابع مشابه
SOX7 is down-regulated in lung cancer
BACKGROUND SOX7 is a transcription factor belonging to the SOX family. Its role in lung cancer is unknown. METHODS In this study, whole genomic copy number analysis was performed on a series of non-small cell lung cancer (NSCLC) cell lines and samples from individuals with epidermal growth factor receptor (EGFR) mutations using a SNP-Chip platform. SOX7 was measured in NSCLC samples and cell ...
متن کامل26S Proteasome Activity Is Down-Regulated in Lung Cancer Stem-Like Cells Propagated In Vitro
Cancer stem cells (CSCs) are a small subset of cancer cells capable of self-renewal and tumor maintenance. Eradicating cancer stem cells, the root of tumor origin and recurrence, has emerged as one promising approach to improve lung cancer survival. Cancer stem cells are reported to reside in the side population (SP) of cultured lung cancer cells. We report here the coexistence of a distinct po...
متن کاملMicroRNA-148b is down-regulated in non-small cell lung cancer and associated with poor survival.
BACKGROUND The aim of this study was to clarify the clinicopathological significance of miRNA-148b (miR-148b) expression in NSCLC, and to explore the correlation between miR-148b level and the prognosis of patients with NSCLC. METHODS 151 patients diagnosed with NSCLC between May 2007 and April 2012 were included in the present study. Real-time RT-PCR method was used to assess the expression ...
متن کاملLncRNA HMlincRNA717 is down-regulated in non-small cell lung cancer and associated with poor prognosis.
INTRODUCTION Long non coding RNAs (lncRNAs) have emerged recently as major players in tumor biology and may be used for cancer diagnosis, prognosis, and potential therapeutic targets. The lncRNA HMlincRNA717, a newly identified lncRNA, was demonstrated to be down-regulated in gastric cancer. However, little is known about its role in non small cell lung cancer (NSCLC). METHODS Expression of l...
متن کامل15-hydroxyprostaglandin dehydrogenase is down-regulated in gastric cancer.
PURPOSE We have investigated the expression and regulation of 15-hydroxyprostaglandin dehydrogenase (15-PGDH) in gastric cancer. EXPERIMENTAL DESIGN Clinical gastric adenocarcinoma samples were analyzed by immunohistochemistry and quantitative real-time PCR for protein and mRNA expression of 15-PGDH and for methylation status of 15-PGDH promoter. The effects of interleukin-1beta (IL-1beta) an...
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ژورنال
عنوان ژورنال: Journal of Experimental & Clinical Cancer Research
سال: 2013
ISSN: 1756-9966
DOI: 10.1186/1756-9966-32-17